Bryan Edward Kolb (born 1947) is a Canadian neuroscientist, neuropsychologist, researcher, author and educator. Kolb's research focuses on the organization and functions of the cerebral cortex.

In 1976, Kolb's PhD thesis established the utility of employing rats for study of the prefrontal cortex in medical research. opening up a new venue for non-primate animal research in the prefrontal cortex and accelerating the development of new treatments