Keratin, type II cytoskeletal 8 also known as cytokeratin-8 (CK-8) or keratin-8 (K8) is a keratin protein that is encoded in humans by the KRT8 gene. It is often paired with keratin 18.

Utility as an immunohistochemical stain

Antibodies to CK8 (e.g. CAM 5.2) can be used to differentiate lobular carcinoma of the breast

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