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Matryona or Matrena is a Russian feminine given name derived from Latin matrona. Diminutive forms: ????, ?????, ???????, ???????, ????????, ????, ????, ??????.

Notable people with the name include:

* Matryona Balk, Russian courtier
* Matrena Nogovitsyna (born 1991), Russian draughts player
* Matryona Necheporchukova (1924-2017),

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