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The rebound effect, also known as the rebound phenomenon, refers to the re-emergence of symptoms that were previously absent or controlled while on medication, which occur when the medication is discontinued or the dosage is reduced. In cases of re-emergence, the symptoms are often more severe than they were before treatment.

Examples

Alpha-2 adrenergic agents

Rebound hypertension, above pre-treatment level, was observed after clonidine and

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