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The triple test, also called triple screen, the Kettering test or the Bart's test, is an investigation performed during pregnancy in the second trimester to classify a patient as either high-risk or low-risk for chromosomal abnormalities (and neural tube defects).

The term "multiple-marker screening test" is sometimes used instead. This term can encompass the "double test" and "quadruple test" (described below).

The Triple screen measures serum

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