Anisometropia is a condition in which a person's eyes have substantially differing refractive power. Generally, a difference in power of one diopter (1D) is the threshold for diagnosis of the condition. Patients may have up to 3 diopters of anisometropia before the condition becomes clinically significant due to headache, eye strain, double vision or photophobia.

In certain types of anisometropia, the visual cortex of the