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<p><b>Granulomatosis with polyangiitis</b> (<b>GPA</b>) is a rare, long-term, <a href="page.php?w=Systemic_disease">systemic disorder</a> that involves the formation of <a href="page.php?w=granuloma">granuloma</a>s and <a href="page.php?w=vasculitis">inflammation of blood vessels</a> (vasculitis). It is an <a href="page.php?w=autoimmune_disease">autoimmune disease</a> and a form of vasculitis that affects small- and medium-sized vessels in many organs, but most commonly affects the upper respiratory tract, lungs, and kidneys. The signs and symptoms</p><p>
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