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<p><b>Scleroderma</b> is a group of <a href="page.php?w=autoimmune_disease">autoimmune disease</a>s that may result in changes to the <a href="page.php?w=human_skin">skin</a>, <a href="page.php?w=blood_vessels">blood vessels</a>, <a href="page.php?w=muscles">muscles</a>, and <a href="page.php?w=internal_organ">internal organ</a>s. The disease can be either localized to the skin or involve other organs as well. Symptoms may include areas of thickened skin, stiffness, feeling tired, and poor blood flow to the fingers or toes with cold exposure. One</p><p>
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