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to as the "assembly domain", and it is required for the initiation of fibronectin matrix assembly. Modules III_9-10 correspond to the "cell-binding domain" of fibronectin. The RGD sequence (Arg-Gly-Asp) is located in III₁₀ and is the site of cell attachment via ?5?1 and ?V?3 integrins on the cell surface. The "synergy site" is in III₉ and has a role in modulating fibronectin's

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