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<p>shown to originate from the precise location of the Spemann organizer which then traverses the presumptive neural epithelium and a full working model of how primary neural inductions was proposed in 2006. There has long been a general reluctance in the field to consider the possibility that primary neural induction might be initiated by mechanical effects. A full explanation for primary neural induction remains yet to be found.</p>

<p><big> Shape change </big></p>
<p>As neurulation proceeds after induction, the cells of the neural plate become <a href="page.php?w=high-columnar">high-columnar</a></p><p>
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