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but are generally brick- or oval-shaped. The virion is exceptionally large, its size ranges from 220-450nm long, 140-260nm wide, and 140-260nm thick, this is likely due to poxviruses encoding all of the vitally needed proteins for their self-sufficient DNA replication and transcription. By comparison, rhinoviruses are 1/10 as large as a typical Poxviridae virion. The genome is a single, linear, double-stranded segment of DNA. On the outer surface membrane it has randomly arranged

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