to the small size of the genome of most endosymbionts, they are unable to exist for any length of time outside of the host cell, thereby preventing a long-term symbiotic relationship. However, in the case of the endonuclear symbiotic bacterium Holospora, it has been discovered that Holospora species can maintain their infectivity for a limited time and form a symbiotic relationship with Paramecium species.

Plants and rhizobial bacteria

There is a mutualistic relationship between legumes and rhizobial bacteria enabling the plants

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