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<p>Researchers engineer an artemisinin precursor pathway in E. coli.</p>

<p><b>2004</b>: First international conference for synthetic biology, Synthetic Biology 1.0 (SB1.0) is held at MIT.</p>

<p><b>2005</b>: Researchers develop a light-sensing circuit in E. coli. Another group designs circuits capable of multicellular pattern formation.</p>

<p><b>2006</b>: Researchers engineer a synthetic circuit that promotes bacterial invasion of tumour cells.</p>

<p><b>2010</b>: Researchers publish in Science the first synthetic bacterial genome, called</p><p>
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