of a wedge-shaped defect of the apical ectoderm of the limb bud (AER: apical ectodermal ridge). Polydactyly, syndactyly and cleft hand can occur within the same hand, therefore some investigators suggest that these entities occur from the same mechanism. This mechanism is not yet defined.

Genetics

The cause of cleft hand lies, for what is known, partly in genetics. The inheritance of cleft hand is autosomal dominant

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