sister kinetochore monoorientation, protection of centromeric cohesin and spindle-pole body cohesion and duplication.

In animal cells

The kinetochore is composed of several layers, observed initially by conventional fixation and staining methods of electron microscopy, (reviewed by C. Rieder in 1982) and more recently by rapid freezing and substitution.

thumbThe deepest layer in the kinetochore is the inner

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