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that may respond to noxious cold, noxious heat or more than one noxious stimulus modality (i.e., they are polymodal) . The nerve endings of sensory neurons that respond preferentially to cooling are found in moderate density in the skin but also occur in relatively high spatial density in the cornea, tongue, bladder, and facial skin . The speculation is that lingual cold receptors deliver information that modulates the sense of taste; i.e. some foods

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