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<p>holding voltage, the <a href="page.php?w=operational_amplifier">operational amplifier</a> generates an "error signal", that is the difference between the command potential and the actual voltage of the cell. The <a href="page.php?w=feedback_circuit">feedback circuit</a> passes current into the cell to reduce the error signal to zero. Thus, the clamp circuit produces a current equal and opposite to the ionic current.</p>

<p><big>Variations of the voltage clamp technique</big></p>
<p><big> Two-electrode voltage clamp using microelectrodes </big></p>
<p>The two-electrode</p><p>
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