lead to neurological deterioration. How HSV gains access to the brain is unknown. The virus shows a distinct predilection for certain parts of the brain. Initially, it is present in the limbic cortices. It may then spread to the adjacent frontal and temporal lobes. Damage to specific areas can result in reduced or eliminated ability to encode new explicit memories, giving rise to anterograde amnesia.

Patients with anterograde amnesia may have episodic, semantic, or both types of explicit memory impaired for events after the trauma that