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<p>a 1,4-isomer and the meta prefix to a 1,2-isomer.  It was the German chemist <a href="page.php?w=Carl_Gr%C3%A4be">Karl Gräbe</a> who, in 1869, first used the prefixes ortho-, meta-, para- to denote specific relative locations of the substituents on a disubstituted aromatic ring (namely <a href="page.php?w=naphthalene">naphthalene</a>).  In 1870, the German chemist <a href="page.php?w=Viktor_Meyer">Viktor Meyer</a> first applied Gräbe's nomenclature to <a href="page.php?w=benzene">benzene</a>.  The current nomenclature was introduced by the</p><p>
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