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late 2013, this definition was explained in greater depth in the first book on the exposome.In 2014, the same author revised the definition to include the body's response with its endogenous metabolic processes which alter the processing of chemicals. More recently, evidenced by metabolic exposures in and around the time of pregnancy, the maternal metabolic exposome includes exposures such as maternal obesity/overweight and diabetes, and malnutrition, including high fat/high calorie diets, which are associated with poor fetal, infant and child

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