she is no longer mentioned in Year 22, when he undertook his first major foreign campaign. This is compatible with the 21 years 9 months recorded by Manetho and Josephus, which would place the end of Hatshepsut's reign in Year 22 of Thutmose III.

Dating the beginning of her reign is more difficult. Her father, Thutmose I, began his reign in either 1526 BC or 1506 BC according to the high and low estimates of her reign, although the length of the reigns of Thutmose I and Thutmose II cannot be determined