In 1978, Mizerak became the first American-born player to compete in a professional Snooker event. He competed in the 1978 Canadian Open, Mizerak won his first match, including an 81 break, but lost to Tony Knowles by 9 frames to 7.

Mizerak also played in a series of snooker and pool challenge matches from 1974 to 1990 - televised examples of Mizerak playing snooker