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the kDNA disk but directly adjacent are two complexes of proteins situated 180? from each other and involved in minicircle replication. The network topology of kinetoplast DNA is primarily understood from experiments on C. fasciculata, based on gel electrophoresis of kinetoplasts that have been broken down by restriction enzymes. These experiments indicate that each minicircle is linked to three on average, and that the crystal lattice

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