voltage clamp (TEVC) technique is used to study properties of membrane proteins, especially ion channels. Researchers use this method most commonly to investigate membrane structures expressed in ''Xenopus'' oocytes. The large size of these oocytes allows for easy handling and manipulability.

The TEVC method utilizes two low-resistance pipettes, one sensing voltage and the other injecting current. The microelectrodes are filled with conductive solution and inserted