and in Unicode since version 1.0 they belong to the block "C0 Controls and Basic Latin". In both cases, as well as in ISO/IEC 646, ISO/IEC 8859 and ISO/IEC 10646 they are occupying the positions in hexadecimal notation 41 to 5A for uppercase and 61 to 7A for lowercase.

Not case sensitive, all letters have code words in the ICAO spelling alphabet