(Hipposideros abae), which are believed to be reservoirs for the virus.

Pathogenesis

Although many components encoded by RVFV's RNA play an important role in the virus' pathology, the nonstructural protein encoded on the S segment (NSs) is the only component that has been found to directly affect the host. NSs is hostile and combative against the host interferon (IFNs) antiviral response. IFNs are essential

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