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<p>within the body such as cellular respiration fail to work effectively at higher temperatures, and further increases can lead them to <a href="page.php?w=Denaturation_%28biochemistry%29">denature</a>, reducing their ability to catalyse essential chemical reactions. This loss of enzymatic control affects the functioning of major organs with high energy demands such as the heart and brain. Loss of fluid and electrolytes causes <a href="page.php?w=heat_cramps">heat cramps</a> - slow muscular contraction and severe muscular spasm lasting between one</p><p>
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