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of the enzyme D-?-hydroxybutyrate dehydrogenase on acetoacetate. Upon entering the tissues, beta-hydroxybutyrate is converted by D-?-hydroxybutyrate dehydrogenase back to acetoacetate along with a proton and a molecule of NADH, the latter of which goes on to power the electron transport chain and other redox reactions. ?-Hydroxybutyrate is the most abundant of the ketone bodies, followed by acetoacetate and finally acetone.?-Hydroxybutyrate and acetoacetate can pass through membranes easily, and are therefore a source of energy for the brain,

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