individual.

Calibration

To use molecular clocks to estimate divergence times, molecular clocks need to be "calibrated". This is because molecular data alone does not contain any information on absolute times. For viral phylogenetics and ancient DNA studies--two areas of evolutionary biology where it is possible to sample sequences over an evolutionary timescale--the dates of the intermediate samples can be used to calibrate the molecular clock. However, most phylogenies require that the molecular

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