Similarly, cyclization and aromatization can be introduced via a cyclase, sometimes proceeded by the enol tautomers of the polyketide. These enzymes are not part of the domains of the polyketide synthase. Instead, they are found in gene clusters in the genome close to the polyketide synthase genes.

Classification

Polyketides are a structurally diverse family. There are various subclasses of polyketides including: aromatics,

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