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for synthetic polymers. Because the latter information was difficult to obtain by other methods, GPC came rapidly into extensive use.

Theory and method

SEC is used primarily for the analysis of large molecules such as proteins or polymers. SEC works by trapping smaller molecules in the pores of the adsorbent ("stationary phase"). This process is usually performed within a column, which typically consists of a hollow tube tightly packed with micron-scale polymer beads containing pores of different

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