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<p>to that of the mother when it is given intramuscularly for labor pains has been estimated to be 1:94.</p>

<p><big>Children</big></p>
<p>Its use in children is generally advised against, although it may be done under the supervision of a specialist. On 21 September 2015, the FDA started investigating the safety of tramadol in use in persons under the age of 17. The investigation was initiated because some of these people have experienced slowed or difficult breathing. The FDA lists age under 12 years old as a contraindication.</p>

<p><big>Elderly</big></p>
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