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<p>This domain has a conserved 10-residue Ca<sup>2+</sup>-binding loop strikingly similar to the canonical 12-residue EF-hand loop. <br/>
** The diversity of the structure of the flanking region is illustrated by the discovery of EF-hand-like domains in bacterial proteins. For example, a helix-loop-strand instead of the helix-loop-helix structure is in periplasmic galactose-binding protein (<a href="page.php?w=Salmonella_typhimurium">Salmonella typhimurium</a>, ) or alginate-binding protein (<a href="page.php?w=Sphingomonas">Sphingomonas</a> sp.,</p><p>
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