Evidence

Evidence for the overall mechanism includes:

*No H/D exchange effects. Experiments with C₂D₄ in water generate CD₃CDO, and runs with C₂H₄ in D₂O generate CH₃CHO. Thus, keto-enol tautomerization is not a possible mechanistic step.
* Negligible kinetic isotope effect with fully deuterated reactants (=1.07). Hence hydride transfer is not

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