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transcription factors, are members of the basic-leucine zipper class. cAMP, an inducer of adipogenesis, can promote expression of C/EBP? and C/EBP?. At the early stage of differentiation, the transient increase of C/EBP? and C/EBP? mRNA and protein levels are thought to activate the adipogenic transcription factors, PPAR? and C/EBP?.

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