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RS-SR + 2 Na -> 2 NaSR, followed by protonation of the resulting metal thiolate: NaSR + HCl -> HSR + NaClIn biochemistry labwork, thiols such as ?-mercaptoethanol (?-ME) or dithiothreitol (DTT) serve as reductants through thiol-disulfide exchange. The thiol reagents are used in excess to drive the equilibrium to the right: RS-SR + 2 HOCH2CH2SH <=> HOCH2CH2S-SCH2CH2OH + 2 RSHThe

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