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<p>hydrophobic fatty acid chains anchor the LPS into the bacterial membrane, and the rest of the LPS projects from the cell surface. The lipid A domain is the most bioactive and responsible for much of the toxicity of Gram-negative bacteria. When bacterial cells are <a href="page.php?w=lysis">lysed</a> by the <a href="page.php?w=immune_system">immune system</a>, fragments of membrane containing lipid A may be released into the circulation, causing fever, diarrhea, and possible fatal endotoxic septic shock (a form of <a href="page.php?w=septic_shock">septic shock</a>).</p><p>
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