obtained in both eukaryotic and prokaryotic cells although there were some difficulties in the procedure due to the length of the gene sequence. Thanks to expression and the cloning work, it is possible to obtain large-scale production of spidroin which provides new opportunities for the manufacture of new biomaterials. There have been attempts to generate transgenic tobacco and potato plants that express remarkable amounts of recombinant Nephila clavipes dragline proteins.

Furthermore, fibers developed from spidroin are tolerated in vitro,