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<p>a <a href="page.php?w=microscope">microscope</a> to observe changes in single enzyme molecules as they catalyse their reactions. These measurements either use changes in the <a href="page.php?w=fluorescence">fluorescence</a> of <a href="page.php?w=Cofactor_%28biochemistry%29">cofactors</a> during an enzyme's reaction mechanism, or of <a href="page.php?w=fluorescent_dyes">fluorescent dyes</a> added onto specific sites of the <a href="page.php?w=protein">protein</a> to report movements that occur during catalysis. These studies provide a new view</p><p>
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