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<p>to work concurrently with <a href="page.php?w=topoisomerase">topoisomerase</a>s, which can chemically cleave the phosphate backbone of one of the strands so that it can swivel around the other. <a href="page.php?w=Helicase">Helicase</a>s unwind the strands to facilitate the advance of sequence-reading enzymes such as <a href="page.php?w=DNA_polymerase">DNA polymerase</a>.</p>

<p><big> Representation </big></p>
<p>The most basic way to describe an RNA secondary structure is through a dot bracket notation. Unpaired bases are marked as dots; paired bases</p><p>
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