largest) source of U.S. federal government support for research in high-energy physics, nuclear physics, fusion energy, materials science, and chemical sciences. The Office of Science is estimated to provide 40 percent of the funding for basic research in the physical sciences in the United States. It is also a major source of funding for government-supported research in climate change, geophysics, genomics, life sciences, and science education.

In constant dollars, Office of Science annual budgets