I truly believed at the time. That was to be my field, application of computers to biomedical problems."

Operations research and the RNA Tie Club

Though Ledley had envisioned a career of employing computers to solve biomedical problems as early as the early 1950s, it would be several years before he would pursue that career full-time. At the National Bureau of Standards, Ledley's work was primarily related to solving military problems using the techniques of operations research. For

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