University of California, Berkeley, in the early 1970s. Subsequently, an improved version of SPICE 2 was available in the mid-1970s, especially to support computer-aided design.

PSpice was released in January 1984 and was the first version of U.C. Berkeley SPICE available on an IBM Personal Computer. PSpice later included a waveform viewer and analyzer program called Probe. Subsequent versions improved on performance and moved to DEC/VAX minicomputers, Sun workstations, Apple Macintosh, and Microsoft Windows.