whereas in other species the corpus luteum remains the primary source of progestogens. In the sheep and human, progesterone is the major placental progestogen.

The equine placenta produces a variety of progestogens, primarily 5?-dihydroprogesterone and 5?,20?-tetrahydroprogesterone, beginning on day 60. A complete luteo-placental shift occurs by day 120-150.

Chemistry

The endogenous progestogens are naturally occurring pregnane

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