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<p>of closely related individuals or selfing. Inbreeding may also lead to <a href="page.php?w=inbreeding_depression">inbreeding depression</a> when heterozygosity is minimized to the point where <a href="page.php?w=deleterious_mutation">deleterious mutation</a>s that reduce fitness become more prevalent. Inbreeding depression is a trend in many plants and animals with small populations sizes and increases their risk of extinction. Inbreeding depression is usually taken to mean any immediate harmful effect, on individuals or on the population, of</p><p>
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