PANoptosome complexes. To date, several PANoptosome complexes have been characterized, including ZBP1-, AIM2-, RIPK1-, NLRC5-/NLRP12-, and NLRP3-PANoptosomes. PANoptosis is critical in innate immune responses for host defense, but it has also been implicated in inflammation and pathology in inflammatory diseases, infections, and cancers.

Phagoptosis is cell death resulting from