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<p>hydrogens are substituted for a larger group, additional strain may occur due to <b>diaxial interactions</b> between pairs of substituents occupying the same-orientation axial position, which are typically repulsive due to steric crowding.</p>

<p><big>Boat and twist-boat conformations</big></p>
<p>The boat conformations have higher energy than the chair conformations. The interaction between the two <b>flagpole</b> hydrogens, in particular, generates <a href="page.php?w=steric_strain">steric strain</a>. Torsional strain also exists between the C2-C3</p><p>
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