of melanocytes

Addison's disease

Decrease in blood adrenocortical hormone level causes increased levels of adrenocorticotropic hormone secreted by anterior pituitary gland. As a result, melanocyte-stimulating hormone is induced which causes oral melanosis.

Smoker's melanosis

Increased melanin production to defend against damage from tobacco smoke

Oral melanoacanthoma

Increased number of dendritic melanocytes

Melanocytic nevi

Accumulation of nevus cells at the basal layer

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