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<p>targeting a specific gene with a mutation and then observing what phenotype develops. The mutation can be designed to <a href="page.php?w=Null_allele">inactivate the gene</a> or only allow it to become active under certain conditions. <a href="page.php?w=Conditional_mutation">Conditional mutation</a>s are useful for identifying genes that are normally lethal if non-functional. As genes with similar functions share similar sequences (<a href="page.php?w=Sequence_homology">homologous</a>) it is possible to predict the likely function of a gene</p><p>
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