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<p>Together with a group of signaling molecules called <a href="page.php?w=Rho_family_of_GTPases">Rho GTPases</a>, these polarity complexes can regulate vesicle transport and also control the localization of cytoplasmic proteins primarily by regulating the phosphorylation of phospholipids called <a href="page.php?w=phosphoinositides">phosphoinositides</a>. Phosphoinositides serve as docking sites for proteins at the cell membrane, and their state of phosphorylation determines which proteins can bind.</p>

<p><big> Polarity establishment </big></p>
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